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Bioinformatics. 2018 Jun 1;34(11):1922-1924. doi: 10.1093/bioinformatics/btx840.

Toppar: an interactive browser for viewing association study results.

Author information

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Novo Nordisk Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford OX3 7LE, UK.
UCL Genetics Institute, University College London, London WC1E6BT, UK.
Oxford University Hospitals Trust, Oxford NIHR Biomedical Research Centre, Churchill Hospital, Headington, Oxford OX3 7LE, UK.



Data integration and visualization help geneticists make sense of large amounts of data. To help facilitate interpretation of genetic association data we developed Toppar, a customizable visualization tool that stores results from association studies and enables browsing over multiple results, by combining features from existing tools and linking to appropriate external databases.

Availability and implementation:

Detailed information on Toppar's features and functionality are on our website along with instructions on how to download, install and run Toppar. Our online version of Toppar is accessible from the website and can be test-driven using Firefox, Safari or Chrome on sub-sets of publicly available genome-wide association study anthropometric waist and body mass index data (Locke et al., 2015; Shungin et al., 2015) from the Genetic Investigation of ANthropometric Traits consortium.


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