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BJU Int. 2018 Jun;121(6):945-951. doi: 10.1111/bju.14126. Epub 2018 Feb 4.

Aquablation therapy for symptomatic benign prostatic hyperplasia: a single-centre experience in 47 patients.

Author information

1
USC Institute of Urology, University of Southern California, Los Angeles, CA, USA.
2
Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India.
3
Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA.
4
Department of Urology, Princess of Wales Hospital, Bridgend, UK.

Abstract

OBJECTIVE:

To report procedure process improvements and confirm the preserved safety and short-term effectiveness of a second-generation Aquablation device for the treatment of lower urinary tract symptoms (LUTS) attributable to benign prostatic hyperplasia (BPH) in 47 consecutive patients at a single institution.

PATIENTS AND METHODS:

Aquablation was performed in 47 patients with symptomatic BPH at a single institution. Baseline, peri-operative and 3-month urinary function data were collected.

RESULTS:

The mean (range) patient age was 66 (50-79) years, and transrectal ultrasonography-measured prostate volume was 48 (20-118) mL. A median lobe was present in 25 patients (53%) and eight patients had catheter-dependent urinary retention. The mean (range) total procedure time was 35 (13-128) min and the tissue resection time was 4 (1-10) min. Five Clavien-Dindo grade I/II and five Clavien-Dindo grade III complications were recorded in eight patients. The mean (range) hospital stay was 3.1 (1-8) days and the mean (range) duration of urethral catheterization was 1.9 (1-11) days. The mean International Prostate Symptom Score (IPSS) decreased from 24.4 at baseline to 5 at 3 months; IPSS quality-of-life score decreased from 4.5 to 0.3 points; peak urinary flow rate increased from 7.1 to 16.5 mL/s and post-void residual urine volume decreased from 119 to 43 mL (all P < 0.01).

CONCLUSIONS:

This study confirmed procedure process improvements resulting from system enhancements, with preservation of safety and effectiveness during use of a second-generation device for the treatment of LUTS attibutable to BPH in the largest single-institution study conducted to date.

KEYWORDS:

aquablation; benign prostatic hyperplasia; prospective study; robotics; surgical resection; waterjet

PMID:
29319914
DOI:
10.1111/bju.14126

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