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Pediatr Dermatol. 2018 Mar;35(2):170-181. doi: 10.1111/pde.13382. Epub 2018 Jan 4.

Pediatric psoriasis: Evolving perspectives.

Author information

1
Department of Dermatology, University of California, San Diego School of Medicine and Rady Children's Hospital, San Diego, CA, USA.
2
Department of Pediatrics, University of California, San Diego School of Medicine and Rady Children's Hospital, San Diego, CA, USA.
3
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
4
Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
5
Department of Dermatology, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
6
Pediatric Dermatology, McGovern School of Medicine and Children's Memorial Hermann Hospital, Houston, TX, USA.
7
Department of Pediatrics, Saint Louis University School of Medicine, Cardinal Glennon Children's Hospital, St. Louis, MO, USA.
8
Department of Dermatology, Saint Louis University School of Medicine, Cardinal Glennon Children's Hospital, St. Louis, MO, USA.
9
Department of Dermatology, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
10
Department of Pediatrics, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
11
Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA, USA.

Abstract

BACKGROUND/OBJECTIVES:

Childhood-onset psoriasis is a common skin disorder that has recently received increasing attention, particularly because of its significant medical, social, financial, and psychological burdens and its associated comorbidities. With limited data available and lack of standardized management guidelines for pediatric psoriasis, an expert panel desired to provide an updated critical overview and practical guidance for management of the affected population.

METHODS:

A panel of pediatric dermatologists with extensive experience in pediatric psoriasis defined and prioritized a core set of topics, performed an English-language literature review, prepared critical evaluations and presentations of topic areas, and carried out a consensus meeting and follow-up consensus manuscript.

RESULTS:

The summation of evolving perspectives in pediatric psoriasis includes epidemiology and natural history of the disease, precipitating factors and comorbidities, quality of life and burden of disease, clinical features and disease presentation, differential diagnosis, pathogenesis and treatment, including topical, photo, and systemic therapies.

CONCLUSION:

Pediatric psoriasis is an important immune-mediated inflammatory skin disease with potential for significant impact on affected individuals and their caregivers. Current state-of-the-art care is based primarily on experience and expert consensus, but pediatric data are accumulating and therapeutic options are rapidly evolving.

KEYWORDS:

clinical; disease burden; epidemiology; pediatrics; psoriasis; treatment

PMID:
29314219
DOI:
10.1111/pde.13382
[Indexed for MEDLINE]

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