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Bull Exp Biol Med. 2018 Jan;164(3):330-333. doi: 10.1007/s10517-018-3983-3. Epub 2018 Jan 8.

Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices.

Author information

1
Research Center of Neurology, Moscow, Russia. kvvt_2000@yahoo.com.
2
Research Center of Neurology, Moscow, Russia.

Abstract

A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices. In contrast, the drug exerted no significant effect on intracellular calcium concentration and its dynamics in neurons of hippocampal CA1 pyramidal layer.

KEYWORDS:

Noopept; fluorescence; hippocampus; intracellular calcium

PMID:
29313229
DOI:
10.1007/s10517-018-3983-3
[Indexed for MEDLINE]

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