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Elife. 2018 Jan 8;7. pii: e33792. doi: 10.7554/eLife.33792.

Transforming a transcription factor.

Author information

1
Department of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.

Abstract

A transcription factor that regulates skeleton formation in sea urchin embryos has evolved a new domain that is essential for this process.

KEYWORDS:

Alx1 transcription factor; developmental biology; evolution; evolutionary biology; exon extension; gene duplication; genomics; sea urchins; skeletogenesis; stem cells

PMID:
29309030
PMCID:
PMC5758108
DOI:
10.7554/eLife.33792
[Indexed for MEDLINE]
Free PMC Article

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