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Neuron. 2018 Jan 3;97(1):10-13. doi: 10.1016/j.neuron.2017.12.023.

Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

Author information

1
Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, 72076 Tübingen, Germany; Department of Neurology and Stroke, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany. Electronic address: til.bergmann@uni-tuebingen.de.
2
Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, 72076 Tübingen, Germany; Center for Integrative Neuroscience, University of Tübingen, 72076 Tübingen, Germany. Electronic address: jan.born@uni-tuebingen.de.

Abstract

In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may explain age-related deficits in memory performance. These results also suggest a more general function of PAC in synaptic plasticity.

PMID:
29301097
DOI:
10.1016/j.neuron.2017.12.023
[Indexed for MEDLINE]
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