Format

Send to

Choose Destination
Schizophr Bull. 2018 Aug 20;44(5):1111-1122. doi: 10.1093/schbul/sbx161.

Childhood Trauma Is Associated With Severity of Hallucinations and Delusions in Psychotic Disorders: A Systematic Review and Meta-Analysis.

Author information

1
Psychological Sciences, University of Melbourne, Parkville, Australia.
2
Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia.
3
Centre for Youth Mental Health, The University of Melbourne, Parkville, Australia.
4
Hospital Universitario de Gran Canaria Dr Negrin, Servicio Canario de Salud, Las Palmas de Gran Canaria, Spain.
5
Clinical Services, Port Phillip Prison, Truganina, Australia.

Abstract

Introduction:

Childhood trauma is a risk factor for the development of psychosis. Furthermore, a number of theories propose specific mechanisms by which childhood trauma may contribute to more severe positive and negative psychotic symptoms, some of which are supported empirically. The robustness of this empirical evidence is unclear due to mixed results and methodological limitations of individual studies. A systematic review and meta-analysis of the evidence for associations between childhood trauma and severity of hallucinations, delusions, and negative psychotic symptoms in clinical populations with a diagnosed psychotic disorder is needed.

Method:

A systematic search was conducted. Reference lists of relevant review articles were hand-searched, and authors contacted for data and additional unpublished studies. Study reporting bias and quality was assessed.

Results:

In total, 6667 studies were identified and of these 41 studies met inclusion criteria. Of these, 29 studies (4680 participants) were meta-analyzed. Among individuals with psychosis, childhood trauma was significantly correlated with severity of hallucinations (r = .199, P < .001) and delusions (r = .172, P < .001) but contrary to our hypothesis, not correlated with severity of negative symptoms (r = .049, P = .095). Severity of childhood neglect was correlated with negative symptoms (r = .142, P = .005).

Conclusion:

The results lend support for cognitive and biological theories that traumas in childhood may lead to hallucinations and delusions within psychotic disorders and have important implications for clinical practice.

PMID:
29301025
PMCID:
PMC6101549
[Available on 2019-08-20]
DOI:
10.1093/schbul/sbx161
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center