Format

Send to

Choose Destination
Pain. 2018 Apr;159(4):673-683. doi: 10.1097/j.pain.0000000000001129.

Developing a core outcome domain set to assessing effectiveness of interdisciplinary multimodal pain therapy: the VAPAIN consensus statement on core outcome domains.

Author information

1
Comprehensive Pain Center, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
2
Department of Applied Health Sciences, University of Applied Sciences, Bochum, Germany.
3
Center for Evidence-Based Healthcare, Hospital and Medical Faculty Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
4
Queen Margaret Hospital, Dunfermline, Scotland, United Kingdom.
5
Patient Representative, Rome, Italy.
6
Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
7
Department of Pain Therapy, Amper Kliniken Dachau, Dachau, Germany.
8
Patient Representative, Pelvic Pain Support Network, Poole, United Kingdom.
9
Swedish Association of Physiotherapists, Stockholm, Sweden.
10
Department of Anesthesiology, Pain Medicine and Pain Psychology, Center for Anesthesiology and Intensive Care Medicine, University Medical Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.
11
Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.
12
German Federation of Physiotherapy, Cologne, Germany.
13
Department of Anesthesiology, Lübeck University Medical School, Lübeck, Germany.
14
Research Group Lifestyle and Health, Faculty of Health Care, University of Applied Sciences Utrecht, Utrecht, the Netherlands.
15
German Pain League, Frankfurt/M., Germany.
16
Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, Regional Referral Headache Centre, Sapienza University of Rome, Rome, Italy.
17
Department of Psychology, Health Psychology Section, King's College London, London, United Kingdom.
18
Research and Quality Assessment, Anesthesiology and Pain Medicine.
19
Day Care Unit, DRK Pain Center Mainz, Germany.
20
Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.
21
Patient Federation "SchmerzLOS e.V.," Lübeck, Germany.
22
Division of Epidemiology at School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
23
Patient Representative, Bautzen, Germany.
24
Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, the Netherlands.
25
Department of Epidemiology and Community Medicine, Faculty of Medicine, Ottawa, Canada.
26
Research Group Health Psychology, University of Leuven, Leuven, Belgium.
27
Patient Representative, Berlin, Germany.
28
Brandenburg Medical School, Neuruppin and Witten-Herdecke University, Neuruppin, Germany.

Abstract

Interdisciplinary multimodal pain therapy (IMPT) is a biopsychosocial treatment approach for patients with chronic pain that comprises at least psychological and physiotherapeutic interventions. Core outcome sets (COSs) are currently developed in different medical fields to standardize and improve the selection of outcome domains, and measurement instruments in clinical trials, to make trial results meaningful, to pool trial results, and to allow indirect comparison between interventions. The objective of this study was to develop a COS of patient-relevant outcome domains for chronic pain in IMPT clinical trials. An international, multiprofessional panel (patient representatives [n = 5], physicians specialized in pain medicine [n = 5], physiotherapists [n = 5], clinical psychologists [n = 5], and methodological researchers [n = 5]) was recruited for a 3-stage consensus study, which consisted of a mixed-method approach comprising an exploratory systematic review, a preparing online survey to identify important outcome domains, a face-to-face consensus meeting to agree on COS domains, and a second online survey (Delphi) establishing agreement on definitions for the domains included. The panel agreed on the following 8 domains to be included into the COS for IMPT: pain intensity, pain frequency, physical activity, emotional wellbeing, satisfaction with social roles and activities, productivity (paid and unpaid, at home and at work, inclusive presentism and absenteeism), health-related quality of life, and patient's perception of treatment goal achievement. The complexity of chronic pain in a biopsychosocial context is reflected in the current recommendation and includes physical, mental, and social outcomes. In a subsequent step, measurement instruments will be identified via systematic reviews.

PMID:
29300277
DOI:
10.1097/j.pain.0000000000001129
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center