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Chem Commun (Camb). 2018 Feb 6;54(12):1417-1420. doi: 10.1039/c7cc08242h.

Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands.

Author information

1
Biodesign Institute Center for Innovations in Medicine, Arizona State University, Tempe, Arizona 85281, USA. chris.diehnelt@asu.edu.

Abstract

We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands. This system could be used for rapid development of peptide-based antivirals for other emerging or neglected tropical infectious diseases.

PMID:
29297911
DOI:
10.1039/c7cc08242h
[Indexed for MEDLINE]

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