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World J Gastrointest Oncol. 2017 Dec 15;9(12):497-501. doi: 10.4251/wjgo.v9.i12.497.

Extrapancreatic solid pseudopapillary neoplasm followed by multiple metastases: Case report.

Author information

1
Department of Gastroenterology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
2
Department of Gastroenterology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China. w339812016@csu.edu.cn.

Abstract

Solid pseudopapillary neoplasm (SPN), also known as Gruber-Frantz tumor, is a rare form of neoplasm that almost exclusively occurs in the pancreas and in young females. While the potential of malignancy is low for SPN, these tumors can mimic other diseases and require a meticulous investigation and a standard treatment by total surgical resection. We present an unusual case of SPN arising in the mesentery of a 40-year-old man with subsequent multiple metastases. Histopathological examination showed similar properties of the mesenteric neoplasm to those of SPN in pancreas. Although the mass was surgically removed, the patient died of recurrent disease 4 years after the initial presentation. We speculate that SPN originates from pancreatic progenitor cells. Further histopathological analyses are required for the prediction of SPN recurrence after resection.

KEYWORDS:

Mesentery; Metastasis; Solid pseudopapillary neoplasm

Conflict of interest statement

Conflict-of-interest statement: We have no pertinent financial relationships to disclose.

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