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J Pharm Biomed Anal. 2018 Feb 20;150:420-426. doi: 10.1016/j.jpba.2017.12.044. Epub 2017 Dec 24.

Chemical profiling of Malva verticillata L. by UPLC-Q-TOF-MSE and their antioxidant activity in vitro.

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College of Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, China. Electronic address:
College of Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, China; Inner Mongolia Research Institute of Traditional Mongolian Medicine Engineering Technology, Tongliao, 028000, China.
Department of Applied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.


Malva verticillata L. (M. verticillata) is an edible medicinal plant. Its dry, mature seeds are used in Traditional Mongolian Medicine. Nevertheless, detailed information regarding its chemical composition remains scarce. In this study, nineteen compounds were identified preliminarily using a UPLC-Q-TOF-MSE method. All of the compounds from M. verticillata are reported for the first time. M. verticillata is shown to be a rich source of phenolics, and the total phenolic content in the leaves, stems and seeds is 110.32 ± 3.45 mg GAE/g extract, 97.98 ± 4.19 mg GAE/g extract and 40.85 ± 7.63 mg GAE/g extract, respectively. The leaves are ideal for scavenging ABTS free radicals and possess ferric reducing antioxidant power, and the seeds are ideal for scavenging DPPH free radicals. M. verticillata is a rich source of natural antioxidants. These findings support the notion that M. verticillata is a functional food and can be used in nutraceutical applications.


Antioxidant activity; Chemical composition; Malva verticillata L; UPLC-Q-TOF-MS(E)

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