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Adv Ther. 2018 Jan;35(1):5-11. doi: 10.1007/s12325-017-0655-z. Epub 2017 Dec 28.

An Emerging Treatment Alternative for Anemia in Chronic Kidney Disease Patients: A Review of Daprodustat.

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Lerin Drug Co. Inc., New York, NY, USA.
St. John's University, Jamaica, NY, USA.


This article reviews an emerging therapeutic agent, which is currently in phase III development for the treatment of anemia secondary to chronic kidney disease, covering promising phase II results, drug characteristics, and the current phase III trials, which, if approved, may significantly impact the management of anemia in this patient population.


Anemia; Chronic kidney disease; Daprodustat; Dialysis; Erythropoietin-stimulating agent; HIF-inhibitor; Hematology; Hemoglobin; Nephrology; Non-dialysis

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