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Oral Implantol (Rome). 2017 Nov 30;10(3):335-342. doi: 10.11138/orl/2017.10.3.335. eCollection 2017 Jul-Sep.

Management of the exposure of a dense PTFE (d-PTFE) membrane in guided bone regeneration (GBR): a case report.

Author information

Centre for Integrative Biology (CIBIO), University of Trento, Trento, Italy; IDIS (Institute for Dental & Implant Studies); Department of Neurosciences, University of Padova, Padova, Italy.
IDIS (Institute for Dental & Implant Studies).
Department of Neurosciences, University of Padova, Padova, Italy.
IDIS (Institute for Dental & Implant Studies); Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
CLC Scientific, Vicenza, Italy; Department of Neurosciences, University of Padova, Padova, Italy; IDIS (Institute for Dental & Implant Studies).


Guided bone regeneration (GBR) is a well-established and generally predictable method for repairing alveolar ridge defects and preparing edentulous sites for implant placement. Standard GBR involves filling the space underneath a membrane with autogenous bone or a mixture composed of autogenous bone particles and allogeneic bone tissue or heterologous biomaterials. The use of a barrier membrane for GBR has sometimes been associated with complications, however - reportedly involving exposure, infection, and collapse - and the non-resorbable types of membrane seem to be involved more often than the resorbable solutions. Such complications may be severe enough to defeat the object of the GBR procedure. A non-resorbable high-density polytetrafluoroethylene (d-PTFE) membrane has recently been designed specifically for use in bone-augmentation procedures that seems to assure a good bone regeneration process even when the membrane is exposed to the oral cavity. This case report describes an exposure of a d-PTFE membrane occurring after a maxillary GBR procedure and how it was overcome successfully, enabling implants insertion.


dental implant therapy; guided bone regeneration; heterologous biomaterials; vertical bone augmentation

Conflict of interest statement

Conflicts of interests Dr. Claudio Soldini declares a conflict or interest with the implant brand used in this case report as co-owner for the company CLC Scientific. All the other Authors declare no conflict of interest.

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