Format

Send to

Choose Destination
Int J Neurosci. 2018 Aug;128(8):783-784. doi: 10.1080/00207454.2017.1405953. Epub 2017 Dec 28.

Autonomic dysfunction in a patient with X-linked adrenoleukodystrophy.

Author information

1
a Department of Neurology, Xuan Wu Hospital , Capital Medical University , Beijing , P. R. China.

Abstract

X-linked adrenoleukodystrophy is an inherited disease caused by abnormal accumulation of very long chain fatty acids. The diagnosis of X-linked adrenoleukodystrophy can be confirmed with the mutation of ABCD1 gene. The main symptom of the X-linked adrenoleukodystrophy is spastic paraparesis, and autonomic dysfunction is rare in X-linked adrenoleukodystrophy. Here, we presented an X-ALD case of a 46-year-old Asian male with severe autonomic dysfunction. Impairment of the autonomic nervous system may closely relate to mitochondrial defect.

KEYWORDS:

X-linked adrenoleukodystrophy; autonomic dysfunction; mitochondrial defect

PMID:
29284317
DOI:
10.1080/00207454.2017.1405953
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center