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J Appl Microbiol. 2018 May;124(5):1032-1046. doi: 10.1111/jam.13681. Epub 2018 Feb 2.

Contact killing and antimicrobial properties of copper.

Author information

1
CNRS, LEMTA, UMR 7563, Vandœuvre-lès-Nancy, France.
2
Université de Lorraine, LEMTA, UMR 7563, Vandœuvre-lès Nancy, France.
3
CNRS, UMR 7565, SRSMC, Vandœuvre-lès-Nancy, France.
4
Université de Lorraine, UMR 7565, SRSMC, Nancy, France.
5
ABC Platform®, Nancy, France.
6
Faculté de Médecine, EA 7298, ERAMBO, DESP, Vandœuvre-lès-Nancy, France.

Abstract

With the emergence of antibiotic resistance, the interest for antimicrobial agents has recently increased again in public health. Copper was recognized in 2008 by the United States Environmental Protection Agency (EPA) as the first metallic antimicrobial agent. This led to many investigations of the various properties of copper as an antibacterial, antifungal and antiviral agent. This review summarizes the latest findings about 'contact killing', the mechanism of action of copper nanoparticles and the different ways micro-organisms develop resistance to copper.

KEYWORDS:

antimicrobial properties; contact killing; copper; micro-organisms; resistance

PMID:
29280540
DOI:
10.1111/jam.13681
[Indexed for MEDLINE]

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