Format

Send to

Choose Destination
Liver Transpl. 2018 Feb;24(2):276-281. doi: 10.1002/lt.25004.

Hypothermic machine perfusion in liver transplantation.

Author information

1
From the Center for Liver Disease and Transplantation, Department of Surgery, Columbia University Medical Center, New York, NY.

Abstract

A finite supply of donor organs has led many transplant centers to accept marginal liver allografts with increasing frequency. These allografts may be at higher risk of primary nonfunction, early allograft dysfunction, and other recipient complications following liver transplantation. Machine perfusion preservation is an emerging technology that limits ischemia/reperfusion injury associated with preservation and may lead to improved outcomes following transplantation. Increased used of machine perfusion in liver preservation may permit an expansion of the donor pool. In this review, we examine the major clinical experience of hypothermic machine perfusion in human liver transplantation.Liver Transplantation 24 276-281 2018 AASLD.

PMID:
29278454
DOI:
10.1002/lt.25004
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center