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Nature. 1989 Apr 6;338(6215):478-83.

The Drosophila gene torso encodes a putative receptor tyrosine kinase.

Author information

1
Max-Planck-Institut für Entwicklungsbiologie, Abteilung Genetik, Tübingen, FRG.

Abstract

The maternal gene torso, required for determination of anterior and posterior terminal structures in the Drosophila embryo, was cloned using P-element tagging. Genetic evidence suggests that the action of the gene product is spatially restricted to the terminal regions; the torso messenger RNA, however, is evenly distributed. Structural similarities of the predicted torso protein with growth-factor receptor tyrosine kinases suggest that the spatial restriction of torso activity results from a localized activation of the torso protein at the anterior and posterior egg pole.

PMID:
2927509
DOI:
10.1038/338478a0
[Indexed for MEDLINE]

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