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Int J Legal Med. 2018 Jul;132(4):1167-1184. doi: 10.1007/s00414-017-1766-4. Epub 2017 Dec 22.

Accuracy of the third molar maturity index in assessing the legal age of 18 years: a systematic review and meta-analysis.

Author information

1
Department of Clinics and Social Dentistry, Federal University of Paraíba, Campus I, University City, João Pessoa, Paraíba, 58051-900, Brazil. bianca.santiago@yahoo.com.br.
2
Department of Forensic Medicine and Dentistry, Scientific Policy Institute, Antônio Teotônio Street, Cristo Redentor, João Pessoa, Paraíba, 58071-620, Brazil. bianca.santiago@yahoo.com.br.
3
Department of Clinics and Social Dentistry, Federal University of Paraíba, Campus I, University City, João Pessoa, Paraíba, 58051-900, Brazil.
4
Department of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, Professor Rodolpho Paulo Rocco Street, 325, University City, Rio de Janeiro, 21941-617, Brazil.

Abstract

The age estimation is a complex procedure required in the daily practice of legal medicine. The maturity of third molars stands out by the age of 18 because these teeth are still in development. This systematic review aimed to assess the accuracy of the third molar maturity index (I 3M), proposed by Cameriere et al. (2008), in discriminating whether an individual is under or over 18 years. Seven electronic databases were screened: PubMed, Scopus, ISI Web of Science, Cochrane Library, LILACS, SIGLE, and CAPES. Eligible studies included an assessment of I 3M accuracy at the 0.08 cut-off value. The quality assessment was performed by using QUADAS 2. Three meta-analyses (MA) were accomplished: overall, one for males and another for females. From 2397 articles identified, 16 met the eligibility criteria. Of these, two showed high risk of bias, one in the reference standard domain and the other in the flow and timing domain. The percentage of individuals correctly classified ranged from 72.4 to 96.0%. The overall MA showed pooled sensitivity of 0.86 (0.84 to 0.87; p = 0.0000) and pooled specificity of 0.93 (0.92 to 0.94; p = 0.0000). The AUC (area under the summary receiver operator characteristics curve) and DOR (diagnostic odds ratio) values were, respectively, 0.9652 and 104.68, indicating an overall high discrimination effect. Separately, better results of accuracy were found for males. High heterogeneity was achieved for both sensibility (94.6%) and specificity (88.8%). We conclude that the I 3M is a suitable and useful method for estimating adulthood regarding forensic purposes, regardless of gender.

KEYWORDS:

Age determination by teeth; Forensic dentistry; Legal age; Systematic review; Third molar

PMID:
29273824
DOI:
10.1007/s00414-017-1766-4
[Indexed for MEDLINE]

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