Approaches to single-molecule studies of metalloprotein electron transfer using scanning probe-based techniques

Martin Elliott; D Dafydd Jones

doi:10.1042/BST20170229

Approaches to single-molecule studies of metalloprotein electron transfer using scanning probe-based techniques

Biochem Soc Trans. 2018 Feb 19;46(1):1-9. doi: 10.1042/BST20170229. Epub 2017 Dec 22.

Authors

Martin Elliott¹, D Dafydd Jones²

Affiliations

¹ School of Physics and Astronomy, Cardiff University, Cardiff, CF24 3AA, U.K. martin.elliott@astro.cf.ac.uk.
² School of Biosciences, Cardiff University, Cardiff, CF10 3AT, U.K.

PMID: 29273619
DOI: 10.1042/BST20170229

Abstract

The single-molecule properties of metalloproteins have provided an intensely active research area in recent years. This brief review covers some of the techniques used to prepare, measure and analyse the electron transfer properties of metalloproteins, concentrating on scanning tunnelling microscopy-based techniques and advances in attachment of proteins to electrodes.

Keywords: STM; electron transfer; protein engineering.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Electrodes
Electron Transport
Metalloproteins / chemistry*
Microscopy, Scanning Tunneling / methods*
Molecular Probes / chemistry*
Single Molecule Imaging / methods*

Substances

Metalloproteins
Molecular Probes

Abstract

Publication types

MeSH terms

Substances

Grants and funding