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J Biomed Opt. 2017 Dec;22(12):1-17. doi: 10.1117/1.JBO.22.12.121716.

Optical coherence tomography in gastroenterology: a review and future outlook.

Author information

1
NinePoint Medical, Inc., Bedford, Massachusetts, United States.
2
Mayo Clinics, Division of Gastroenterology and Hepatology, Rochester, Minnesota, United States.
3
North Shore University Hospital and Hofstra Northwell School of Medicine, Division of Gastroenterolo, United States.
4
Columbia University Medical Center, Department of Gastroenterology, New York City, New York, United States.
5
Spaarne Gasthuis and Free University Medical Center, Amsterdam, The Netherlands.
6
Ochsner Clinic Foundation, Department of Gastroenterology, New Orleans, Louisiana, United States.
7
Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands.
8
Veterans Affairs Boston Healthcare System and Harvard Medical School, Department of Gastroenterology, United States.
9
Massachusetts General Hospital, Gastrointestinal Unit, Boston, Massachusetts, United States.

Abstract

Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease detection/differentiation and endoscopic therapy guidance, as well as a discussion of its future applications.

KEYWORDS:

Barrett’s esophagus; endoscopic imaging; gastroenterology; inflammatory bowel disease; optical biopsy; optical coherence tomography; volumetric laser endomicroscopy

PMID:
29260538
DOI:
10.1117/1.JBO.22.12.121716
[Indexed for MEDLINE]
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