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J Arrhythm. 2017 Dec;33(6):643-645. doi: 10.1016/j.joa.2017.08.005. Epub 2017 Oct 2.

Complex regional pain syndrome induced by pacemaker implantation for sick sinus syndrome.

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Heart Center, Kyushu University Hospital, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Faculty of Arts and Science, Kyushu University, Kasuga Kohen 6-1, Kasuga 816-8580, Japan.


A 53-year-old woman reported burning pain, muscle weakness, and dysesthesia of the left arm 2 months after permanent pacemaker insertion in the ipsilateral side for the treatment of sick sinus syndrome. Complex regional pain syndrome (CRPS) induced by pacemaker implantation was diagnosed. In 2017, her pulse generator became exhausted and was exchanged carefully to avoid exacerbation of CRPS, under the application of local anesthesia and premedication. Six months later, the patient's grip strength in her left hand remained lower relative to that in her right hand. Although rare, the presence of CRPS following device implantation should be remembered.


Complex regional pain syndrome; Pain control; Permanent pacemaker implantation

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