[The expression of antigens, detectable with ICO-series monoclonal antibodies, on the surfaces of cells forming granulocyte and macrophage colonies in semiliquid agar]

E V Savel'eva; L A Kharlamova; A Iu Baryshnikov; V A Agafonov; N N Tupitsyn

[The expression of antigens, detectable with ICO-series monoclonal antibodies, on the surfaces of cells forming granulocyte and macrophage colonies in semiliquid agar]

Eksp Onkol. 1989;11(1):46-8.

[Article in Russian]

Authors

E V Savel'eva, L A Kharlamova, A Iu Baryshnikov, V A Agafonov, N N Tupitsyn

PMID: 2924710

Abstract

The expression of antigens on granulocyte-macrophagal colony-forming cells of patients with nonhematological diseases was studied. Treatment of bone marrow cells with murine monoclonal antibodies ICO-1 and ICO-11 led to statistically significant inhibition of the number of growing colonies. Monoclonal antibodies ICO-02, ICO-10, ICO-GM-1 and ICO-G-2 had no such effect.

Publication types

Comparative Study
English Abstract

MeSH terms

Agar
Antibodies, Monoclonal / immunology*
Antigens, Differentiation / analysis*
Antigens, Surface / analysis
Bone Marrow / immunology
Bone Marrow Cells
Cells, Cultured
Colony-Forming Units Assay
Complement System Proteins / immunology
Granulocytes / immunology*
Humans
Macrophages / immunology*
Stem Cells / immunology*

Substances

Antibodies, Monoclonal
Antigens, Differentiation
Antigens, Surface
Agar
Complement System Proteins