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BMC Psychiatry. 2017 Dec 16;17(1):403. doi: 10.1186/s12888-017-1563-0.

The Autism-Tics, ADHD and other Comorbidities inventory (A-TAC): previous and predictive validity.

Author information

1
Centre for Ethics Law and Mental Health (CELAM) Institute of Neuroscience and Physiology, University of Gothenburg, SU Rättspsykiatri, Rågårdsvägen 5, Enhet CELAM Hus 1, SE-424 57 Gunnilse, Gothenburg, Sweden. caroline.marland@vgregion.se.
2
Department of Forensic Psychiatry, Sahlgrenska University Hospital, SU Rättspsykiatri, Rågårdsvägen 5, SE-424 57 Gunnilse, Gothenburg, Sweden. caroline.marland@vgregion.se.
3
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77, Stockholm, Sweden.
4
Centre for Ethics Law and Mental Health (CELAM) Institute of Neuroscience and Physiology, University of Gothenburg, SU Rättspsykiatri, Rågårdsvägen 5, Enhet CELAM Hus 1, SE-424 57 Gunnilse, Gothenburg, Sweden.
5
Department of Forensic Psychiatry, Sahlgrenska University Hospital, SU Rättspsykiatri, Rågårdsvägen 5, SE-424 57 Gunnilse, Gothenburg, Sweden.
6
Department of Clinical Sciences, Lund University, Box 117, SE-221 00, Lund, Sweden.
7
Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, SE-411 19, Göteborg, Sweden.

Abstract

BACKGROUND:

Reliable and easy to administer screening instruments focusing on neurodevelopmental disorders and associated conditions are scarce. The Autism-Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated and reporting good- excellent validity for several disorders. This article aims to expand these findings by including more conditions in a substantially larger sample augmented with the Swedish National Patient Register (NPR).

METHODS:

Since 2004 parents of all 9-year-old Swedish twins have been invited to participate in a telephone interview in the Child and Adolescent Twin Study in Sweden, CATSS. The CATSS is linked to the NPR which includes data from in- and outpatient care. Data on neurodevelopmental disorders (A-TAC) collected in CATSS were compared with diagnoses from the NPR. We investigated diagnoses that had been made both before (previous validity) and after (predictive validity) the interview.

RESULTS:

Sensitivity and specificity of A-TAC scores for predicting earlier or later clinical diagnoses were mostly good-excellent, with values of the area under the curve for a clinical diagnosis of autism spectrum disorder (ASD) of .98, attention deficit hyperactivity disorder (ADHD) .93, learning disorder (LD) .92, and oppositional defiant disorder (ODD) .99, with small differences in terms of previous and predictive analyses. A-TAC provided little validity for eating disorders.

CONCLUSION:

The result support previous claims: A-TAC is a broad screening instrument with a particular strength in assessing ASD, ADHD, LD, and ODD at ages 9 and 12, and also provides phenotypic information about other child psychiatric disorders.

KEYWORDS:

ADHD; Autism; Neurodevelopmental disorders; Screening

PMID:
29246205
PMCID:
PMC5732476
DOI:
10.1186/s12888-017-1563-0
[Indexed for MEDLINE]
Free PMC Article

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