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J Wound Care. 2017 Dec 2;26(12):778-783. doi: 10.12968/jowc.2017.26.12.778.

Developing antimicrobial calcium alginate fibres from neem and papaya leaves extract.

Author information

1
Lecturer, Department of Materials and Testing, National Textile University, Faisalabad 37610, Pakistan.
2
Lecturer, Department of Textile Engineering, Bahauddin Zakariya University, Multan 59060, Pakistan.
3
Assistant Professor, Faculty of Engineering and Technology, National Textile University, Faisalabad 37610, Pakistan.

Abstract

OBJECTIVE:

The aim of this study was to evaluate an alternative approach to developing antimicrobial alginate fibres using plant extracts, such as those from neem and papaya leaves.

METHOD:

Aqueous leaves extract from neem, papaya and their hybrid combinations were used as solvent to develop sodium alginate fibres. Sodium alginate polymer containing these extracts was extruded in a calcium chloride (CaCl2) bath to develop neem (NE), papaya (PE) and their hybrid combinations-based calcium alginate fibres (H-1 to H-5). The surface morphology, spectra, liquid absorption, tensile strength and antimicrobial activity of these developed fibres were measured.

RESULTS:

NE fibre showed greater tensile strength than PE. The liquid absorption property of all developed fibres decreased, but showed antibacterial properties against Staphylococcus aureus and reduced bacterial growth up to 85% when compared with pure calcium alginate fibre.

CONCLUSION:

Neem, papaya and hybrid extract-based calcium alginate fibres have the potential to be used as wound dressings.

KEYWORDS:

antimicrobial fibre; calcium alginate; herbal extracts; hybrid extract-based fibre; wound care

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