Patient-Paired Sample Congruence Between 2 Commercial Liquid Biopsy Tests

Gonzalo Torga; Kenneth J Pienta

doi:10.1001/jamaoncol.2017.4027

Patient-Paired Sample Congruence Between 2 Commercial Liquid Biopsy Tests

JAMA Oncol. 2018 Jun 1;4(6):868-870. doi: 10.1001/jamaoncol.2017.4027.

Authors

Gonzalo Torga¹, Kenneth J Pienta¹

Affiliation

¹ The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Abstract

This cohort study examines the reliability and potential utility of 2 commercially available liquid biopsy assays for reported mutations in cell-free DNA.

Publication types

Comparative Study

MeSH terms

Adenocarcinoma / blood
Adenocarcinoma / genetics
Adenocarcinoma / secondary*
Cell-Free Nucleic Acids / blood*
DNA Mutational Analysis
DNA, Neoplasm / blood*
Exons / genetics
Genes, Neoplasm
Humans
Liquid Biopsy / methods*
Male
Prostate-Specific Antigen / blood
Prostatic Neoplasms / blood*
Prostatic Neoplasms / genetics
Reproducibility of Results
Sensitivity and Specificity
Sequence Analysis, DNA / methods

Substances

Cell-Free Nucleic Acids
DNA, Neoplasm
Prostate-Specific Antigen