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Ann Med. 1989 Feb;21(1):59-62.

Antioxidants and platelets.

Author information

1
Department of Community Health and General Practice, University of Kuopio, Finland.

Abstract

It is postulated that antioxidants reduce platelet activity by the stimulation of prostacyclin synthetase by scavenging synthesis-inhibiting peroxides. The experimental and clinical evidence supporting this theory is inconclusive. Clinical trials suggest that vitamin E reduced platelet aggregability. Nonexperimentally, a strong association has been observed between low serum selenium concentration and increased platelet aggregability. These findings suggest that antioxidants have an important role in the regulation of platelet function.

PMID:
2923705
DOI:
10.3109/07853898909149183
[Indexed for MEDLINE]

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