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Kidney Blood Press Res. 2017;42(6):1119-1127. doi: 10.1159/000485779. Epub 2017 Dec 7.

Comparison of Muscle Mass Indices Using Computed Tomography or Dual X-Ray Absorptiometry for Predicting Physical Performance in Hemodialysis Patients.

Author information

1
Division of Nephrology, Department of Internal Medicine, Yeungnam University Hospital, Daegu, Republic of Korea.
2
Department of Radiology, CHA Gumi Medical Center, CHA University, Gumi-si, Republic of Korea.
3
Division of Nephrology, Department of Internal Medicine, Semyung Christianity Hospital, Pohang-si, Republic of Korea.
4
Division of Nephrology, Department of Internal Medicine, CHA Gumi Medical Center, CHA University, Gumi-si, Republic of Korea.

Abstract

BACKGROUND/AIMS:

Our study aims to evaluate the association between thigh muscle cross-sectional area (TMA) using computed tomography (CT), or appendicular skeletal muscle mass (ASM) using dual energy X-ray absorptiometry (DEXA), and physical performance levels in hemodialysis (HD) patients.

METHODS:

Patients were included if they were on HD for ≥6 months (n = 84). ASM and TMA were adjusted to body weight (BW, kg) or height2 (Ht2, m2). Each participant performed a short physical performance battery test (SPPB), a sit-to-stand for 30 second test (STS30), a 6-minute walk test (6-MWT), a timed up and go test (TUG), and hand grip strength (HGS) test.

RESULTS:

Correlation coefficients for SPPB, GS, 5STS, STS30, 6-MWT, and TUG were highest in TMA/BW. Results from partial correlation or linear regression analyses displayed similar trends to those derived from Pearson's correlation analyses. An increase in TMA/BW or TMA/Ht2 was associated with a decreased odds ratio of low SPPB, GS, or HGS in multivariate analyses. Indices using DEXA were associated with a decreased odds ratio of a low HGS only in multivariate analysis.

CONCLUSION:

TMA indices using CT may be more valuable in predicting physical performance or strength in HD patients.

KEYWORDS:

Appendicular muscle mass; Hemodialysis; Physical performance; Thigh muscle cross-sectional area

PMID:
29224021
DOI:
10.1159/000485779
[Indexed for MEDLINE]
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