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Cell Stem Cell. 2017 Dec 7;21(6):707-708. doi: 10.1016/j.stem.2017.11.014.

Plasticity in Olfactory Epithelium: Is It a Sniffer or Shape Shifter?

Author information

1
Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA; Medical Scientist Training Program, Duke University School of Medicine, Durham, NC 27710, USA.
2
Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA; Regeneration Next, Duke University, Durham, NC 27710, USA. Electronic address: purushothamarao.tata@duke.edu.

Abstract

Precise lineage trajectories and the cellular sources that contribute to regeneration after injury are largely unknown in many tissues. In this issue of Cell Stem Cell, Gadye et al. (2017) and Lin et al. (2017) show that olfactory epithelial cells transit through unique and unfamiliar paths of differentiation and undergo lineage reversion, respectively, during regeneration.

PMID:
29220660
DOI:
10.1016/j.stem.2017.11.014
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