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Dement Neuropsychol. 2009 Jul-Sep;3(3):241-247. doi: 10.1590/S1980-57642009DN30300011.

Quality of life and Alzheimer's disease: Influence of participation in a rehabilitation center.

Author information

B.S., Gerontology, Day Hospital Rehabilitation Center (CRHD), Department and Institute of Psychiatry (IPq), Faculty of Medicine (FMUSP), University of São Paulo, São Paulo, SP, Brazil.
M.D., PhD in Psychiatry, University of São Paulo, São Paulo, SP, Brazil.
M.D., Geriatrics, Joint Professor and PhD, Department of Clinical Medicine, University of Sao Paulo, São Paulo, SP, Brazil.
PhD in Developmental Psychology; Assistant Professor of Gerontology, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, SP, Brazil.


in English, Portuguese

Quality of life is seldom explored in evaluations of therapeutic interventions in Alzheimer's disease.


To verify whether participation in a cognitive and functional rehabilitation program improves quality of life (QOL) among Alzheimer's disease (AD) patients.


19 AD patients participated in this study, 12 of whom attended 24 multi-professional intervention sessions - the experimental group - whereas the remaining 7 comprised the control group. The following tools were used to assess changes: a) Mini-Mental State Examination (MMSE); b) Geriatric Depression Scale (GDS); c) Quality of Life in AD evaluation scale (QOL-AD); d) Open question on QOL.


Participation had no positive impact on quantitative clinical variables (MMSE, GDS, QOL-AD). The answers to the open question, examined using the Collective Subject Discourse (CSD) method, suggested that QOL improved after the intervention.


Combining pharmacological treatment with psychosocial intervention may prove to be an effective strategy to enhance the QOL of AD patients.


Alzheimer’s disease; psychosocial intervention; quality of life

Conflict of interest statement

Disclosure: The authors report no conflicts of interest.

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