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Lipids Health Dis. 2017 Dec 6;16(1):233. doi: 10.1186/s12944-017-0625-0.

Hypertriglyceridemia and atherosclerosis.

Author information

1
Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China.
2
Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China. lixp0040@csu.edu.cn.

Abstract

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk. But the proatherogenic mechanism of triglyceride (TG) remains unclear. Therefore, this article focuses on the clinical studies and proatherogenic mechanism related to hypertriglyceridemia, in order to provide reference for the prevention and treatment of ASCVD.

KEYWORDS:

Atherosclerosis; Atherosclerotic cardiovascular disease; Lipoprotein; Triglyceride

PMID:
29212549
PMCID:
PMC5719571
DOI:
10.1186/s12944-017-0625-0
[Indexed for MEDLINE]
Free PMC Article

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