A Study of Correlation of Neck Circumference with Framingham Risk Score as a Predictor of Coronary Artery Disease

J Clin Diagn Res. 2017 Sep;11(9):OC17-OC20. doi: 10.7860/JCDR/2017/25710.10609. Epub 2017 Sep 1.

Abstract

Introduction: It has been observed that metabolic syndrome is risk factor for Coronary Artery Disease (CAD) and exerts its effects through fat deposition and vascular aging. CAD has been acknowledged as a leading cause of death. In earlier studies, the metabolic risk has been estimated by Framingham risk score. Recent studies have shown that Neck Circumference (NC) has a good correlation with other traditional anthropometric measurements and can be used as marker of obesity. It also correlates with Framingham risk score, which is slightly more sophisticated measure of CAD risk.

Aim: To assess the risk of CAD in a subject based on NC and to correlate the NC to Framingham risk score.

Materials and methods: The present cross-sectional study, done at Karnataka Institute of Medical Sciences, Hubli, Karnataka, India, includes 100 subjects. The study duration was of one year from 1st January 2015 to 31st December 2015. Anthropometric indices Body Mass Index (BMI) and NC were correlated with 10 year CAD risk as calculated by Framingham risk score. The correlation between BMI, NC, vascular age and Framingham risk score was calculated using Karl Pearson's correlation method.

Results: NC has a strong correlation with 10 year CAD risk (p≤0.001). NC was significantly greater in males as compared to females (p≤0.001). Males had greater risk of cardiovascular disease as reflected by higher 10 year Framingham risk score (p≤0.0035).

Conclusion: NC gives simple and easy prediction of CAD risk and is more reliable than traditional risk markers like BMI. NC correlates positively with 10 year Framingham risk score.

Keywords: Fat deposition; Ischemic heart disease (IHD); Risk stratification.