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Clin Neurophysiol. 2018 Jan;129(1):238-245. doi: 10.1016/j.clinph.2017.11.006. Epub 2017 Nov 21.

Clinical features of otolith organ-specific vestibular dysfunction.

Author information

1
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: cfujimoto-tky@umin.ac.jp.
2
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: sayasuzuki-tky@umin.ac.jp.
3
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: kinoshitam-zao@umin.ac.jp.
4
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: n-egami@umin.ac.jp.
5
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: keisuga-tky@umin.ac.jp.
6
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: iwashin-tky@umin.ac.jp.

Abstract

OBJECTIVE:

To elucidate the clinical features and vestibular symptoms of patients with otolith organ dysfunction in the presence of normal function of the semicircular canals.

METHODS:

We reviewed the clinical records of 277 consecutive new patients with balance disorders who underwent testing of cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs) as well as caloric testing and video head impulse testing (vHIT).

RESULTS:

We identified 76 patients who showed normal caloric responses and normal vHIT findings in each SCC plane, but abnormal responses in cVEMP and/or oVEMP testing. Benign paroxysmal positional vertigo (BPPV) was the most common diagnosis. 37% of patients could not be categorized into any of the established clinical entities that could cause a balance disorder and did not show sensorineural hearing loss. The most common clinical manifestation in the idiopathic cases was recurrent rotatory vertigo with a duration of 1-12 h.

CONCLUSIONS:

The most common diagnosis of otolith organ-specific vestibular dysfunction was BPPV. The most common clinical manifestation in the idiopathic cases was recurrent rotatory vertigo.

SIGNIFICANCE:

Specific dysfunction of the otolith organs occurs in association with some of the undiagnosed patients with recurrent rotatory vertigo.

KEYWORDS:

Saccule; Utricle; Vertigo; Vestibular diseases; Vestibule

PMID:
29207275
DOI:
10.1016/j.clinph.2017.11.006
[Indexed for MEDLINE]

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