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Biochim Biophys Acta Mol Basis Dis. 2018 Mar;1864(3):843-850. doi: 10.1016/j.bbadis.2017.11.027. Epub 2017 Dec 2.

FTO demethylase activity is essential for normal bone growth and bone mineralization in mice.

Author information

1
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK. Electronic address: gregor.sachse@dpag.ox.ac.uk.
2
MRC Harwell Institute, Mammalian Genetics Unit and Mary Lyon Centre, Harwell Campus, Oxfordshire, OX11 0RD, UK. Electronic address: churchc@MedImmune.com.
3
MRC Harwell Institute, Mammalian Genetics Unit and Mary Lyon Centre, Harwell Campus, Oxfordshire, OX11 0RD, UK. Electronic address: m.stewart@har.mrc.ac.uk.
4
MRC Harwell Institute, Mammalian Genetics Unit and Mary Lyon Centre, Harwell Campus, Oxfordshire, OX11 0RD, UK. Electronic address: h.cater@har.mrc.ac.uk.
5
MRC Harwell Institute, Mammalian Genetics Unit and Mary Lyon Centre, Harwell Campus, Oxfordshire, OX11 0RD, UK. Electronic address: l.teboul@har.mrc.ac.uk.
6
MRC Harwell Institute, Mammalian Genetics Unit and Mary Lyon Centre, Harwell Campus, Oxfordshire, OX11 0RD, UK. Electronic address: r.cox@har.mrc.ac.uk.
7
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK. Electronic address: frances.ashcroft@dpag.ox.ac.uk.

KEYWORDS:

Body composition; Body size; Bone mineralization; FTO protein; Mouse model

PMID:
29203346
PMCID:
PMC5798602
DOI:
10.1016/j.bbadis.2017.11.027
[Indexed for MEDLINE]
Free PMC Article

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