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J Med Vasc. 2017 Dec;42(6):375-383. doi: 10.1016/j.jdmv.2017.09.006. Epub 2017 Nov 15.

[New international guidelines for curative treatment and prophylaxis for venous thromboembolism (VTE) in cancer patients and the dedicated smartphone application].

[Article in French]

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UF04 maladies auto-immunes et pathologie vasculaire, service de médecine interne, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris, 1, avenue Claude-Vellefaux, 75010 Paris, France.
Service de médecine interne, CHU de Nantes, 44000 Nantes, France.
Service de médecine vasculaire, hôpital Saint-André, 33076 Bordeaux, France.
Service de médecine vasculaire, groupe hospitalier Paris Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France.
Service d'oncologie médicale, centre Henri-Becquerel, rue d'Amiens, 76000 Rouen, France.
Département de médecine interne et gériatrie, centre hospitalier universitaire de Treichville, université Félix Houphouet Boigny d'Abidjan, Abidjan, Côte d'Ivoire.
Service d'oncologie médicale, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris, 1, avenue Claude-Vellefaux, 75010 Paris, France.
Service d'hématologie biologique, hôpital Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75013 Paris, France. Electronic address:


Venous thromboembolism (VTE) is a frequent and serious complication in cancer patients, and the second leading cause of death in this setting. Cancer patients are also more likely to present recurrent VTE and major bleeding while taking anticoagulants. Management of VTE in these patients is always challenging and remains suboptimal worldwide. In 2013, the International Initiative on Thrombosis and Cancer (ITAC-CME) released international guidelines for the treatment and prophylaxis of VTE and central venous catheter-associated thrombosis, based on a systematic review of the literature ranked according to the Grading of Recommendations Assessment, Development, and Evaluation scale. An update of these ITAC-CME consensus guidelines, including the use of direct oral anticoagulants, was recently published. In this review, we summarize these updated guidelines. Better adherence to the international guidelines, involving an adequate educational and active implementation strategies, will substantially decrease the burden of VTE and allow to increase survival in cancer patients.


Cancer; Guidelines; Héparines de bas poids moléculaire; Low-molecular-weight heparins; Maladie thromboembolique veineuse; Recommandations; Traitement; Treatment; Venous thromboembolism

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