Format

Send to

Choose Destination
Genome Med. 2017 Dec 4;9(1):107. doi: 10.1186/s13073-017-0501-6.

Emerging mechanisms and novel targets in allergic inflammation and asthma.

Author information

1
Harvard Medical School and Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA. scott.weiss@channing.harvard.edu.

Abstract

Airway inflammation is key to the severity and persistence of asthma. Recent studies have revealed novel immune mechanisms that target dendritic cells, T helper 2 cytokines, regulatory T cells, and type 2 innate lymphoid cells in allergic inflammation, as well as novel approaches that target airway smooth muscle in asthma. These advances inform the development of new targeted treatments for allergic inflammation and asthma with the potential to provide therapeutic benefit.

PMID:
29202803
PMCID:
PMC5713157
DOI:
10.1186/s13073-017-0501-6
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center