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Indian J Med Paediatr Oncol. 2017 Jul-Sep;38(3):349-353. doi: 10.4103/ijmpo.ijmpo_84_16.

Round Cell Tumors: Classification and Immunohistochemistry.

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Department of Conservative Dentistry and Endodontics, Eklavya Dental College and Hospital, Kotputli, Rajasthan, India.
Department of Oral Medicine and Radiology, ESIC PGIMSR Medical College and Hospital, Bengaluru, Karnataka, India.
PDM Dental College and Research Institute, Bahadurgarh, Haryana, India.
Oral Pathology Division Oral Basic Clinical Sciences, College of Dentistry, Qassim Private Colleges, Buraidah 51411, KSA.
Department of Pedodontics, RR Dental College, Udaipur, Rajasthan, India.
BRS Dental College and Hospital, Sultanpur, Haryana, India.
Department of Oral Medicine and Radiology, Institute of Dental Sciences and Sum Hospital, Bhubaneswar, Odisha, India.
Private Practioner, Lajpat Nagar, New Delhi, India.


Round cell tumors as the name suggest are comprised round cells with increased nuclear-cytoplasmic ratio. This group of tumor includes entities such as peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, neuroblastoma, hepatoblastoma, Wilms' tumor, and desmoplastic small round cell tumor. These round cells tumors are characterized by typical histological pattern, immunohistochemical, and electron microscopic features that can help in differential diagnosis. The present article describes the classification and explains the histopathology and immunohistochemistry of some important round cell tumors.


Ewing sarcoma; lymphoma; round cell tumor

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