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Rev Med Inst Mex Seguro Soc. 2017 Sep-Oct;55(5):666-670.

[Disseminated tuberculosis in a patient with overlap syndrome, challenges in preventing].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

Subdirección de Enseñanza e Investigación, Hospital Regional de Alta Especialidad de Oaxaca, San Bartolo Coyotepec, Oaxaca, México


in English, Spanish

Patients with autoimmune rheumatic diseases are at increased risk for developing infections and these are associated with increased morbidity and mortality from these diseases, especially in patients with systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis and autoimmune inflammatory myopathies. The objective of this paper is to address the challenges in detecting latent tuberculosis in immunosuppressed patients and the initiation of prophylactic treatment because currently there are no well-defined guidelines indicating what action to take for detection and treatment; so far the available scientific evidence is scarce and some methodological shortcomings.


Latent tuberculosis ; Rheumatic diseases ; Tuberculin test; Tuberculosis

[Indexed for MEDLINE]

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