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Rev Med Inst Mex Seguro Soc. 2017 Nov-Dec;55(6):708-714.

[Effect of exercise on the serum concentrations of leptin and adiponectin in adolescents with risk factors of developing diabetes].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Cuerpo Académico Salud del Universitario, Centro de Investigación en Ciencias Médicas (CICMED), Universidad Autónoma del Estado de México, Toluca, Estado de México jjgg1977@hotmail.com.

Abstract

in English, Spanish

BACKGROUND:

Type 2 diabetes mellitus (T2DM) is an increasing health issue. Physical activity (PA) in early stages is a preventive measure in the development of degenerative diseases. It has been documented the association between exercise and leptin and adiponectin concentrations. The objective was to evaluate the effect of a physical activity program (PAP) on serum leptin and adiponectin in teenagers with risk factors for developing T2DM.

METHODS:

Experimental-longitudinal study. Teenagers (men and women), with T2DM risk factors, aged 14 to 16 years, participated in a PAP for three months, five days a week, 45 minutes each day. Before and after the program, all anthropometric variables, incluiding leptin and adiponectin, were evaluated.

RESULTS:

22 adolescents participated in the PAP and they were compared with 22 adolescents from the control group (who did not participate in the PAP). There was a reduction in the serum concentration of leptin in the intervention group (baseline 23 ± 13; after the PAP 14 ± 8, p > 0.0001), compared with the control group (baseline 18 ± 13, three months follow-up 20 ± 14, p < 0.520). Also, the adiponectin concentration increased (baseline 10 ± 3, after the PAP 13 ± 4.0, p > 0.014), compared with the control group (baseline 11 ± 3, 13 ± 4.0 after the PAP p > 0.032).

CONCLUSIONS:

This study support the efficacy of an aerobic exercise intervention on metabolic markers of adolescents with risk factors for developing diabetes.

KEYWORDS:

Adiponectin; Leptin; Diabetes Mellitus Type 2; Adolescent; Exercise

PMID:
29190863
[Indexed for MEDLINE]

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