Format

Send to

Choose Destination
PLoS One. 2017 Nov 30;12(11):e0185343. doi: 10.1371/journal.pone.0185343. eCollection 2017.

Association between grip strength and hand and knee radiographic osteoarthritis in Korean adults: Data from the Dong-gu study.

Author information

1
Department of Rheumatology, Chonnam National University Medical School & Hospital, Gwangju, Republic of Korea.
2
Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju, Republic of Korea.
3
Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
4
Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea.
5
Department of Preventive Medicine & Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Republic of Korea.
6
Department of Preventive Medicine, Bitgoeul Chonnam National University Hospital, Gwangju, Republic of Korea.

Abstract

OBJECTIVES:

We assessed whether grip strength was related to various types of radiographic damage in Korean adults with osteoarthritis (OA).

METHODS:

Data from 2,251 subjects enrolled in the Dong-gu study, who had no hand joint pain, were analyzed to investigate the relationship between grip strength and OA. Hand grip strength was measured using a hand-held dynamometer, and radiographs of the hand and knee were scored according to a semi-quantitative grading system. Multiple linear regressions were used to explore associations between grip strength and radiographic features of OA.

RESULTS:

Grip strength in men and women was negatively related to hand (both p < 0.001) and knee (men, p < 0.001; women, p = 0.010) OA after adjusting for confounders. Hand (men, p < 0.001; women, p = 0.001) and knee (both p < 0.001) joint space narrowing (JSN) showed the strongest associations with low grip strength, regardless of gender. Moreover, the severity of hand osteophytes in women (p = 0.001), and subchondral cysts (men, p < 0.001) was correlated with low grip strength in both genders.

CONCLUSIONS:

Among subjects without hand joint pain, low grip strength was associated significantly with hand and knee radiographic OA, regardless of gender. Among all types of OA radiographic damage, low grip strength showed the strongest association with JSN.

PMID:
29190722
PMCID:
PMC5708816
DOI:
10.1371/journal.pone.0185343
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Public Library of Science Icon for PubMed Central
Loading ...
Support Center