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Int J Impot Res. 2018 Feb;30(1):1-7. doi: 10.1038/s41443-017-0002-6. Epub 2017 Nov 27.

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy: a review of preclinical studies.

Author information

1
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
2
Department of Urology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China. fyyyruigao@163.com.
3
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. yipinglu@163.com.

Abstract

Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel treatment for erectile dysfunction (ED). Its ability to improve erectile function has been shown in patients with vasculogenic ED by many randomized-controlled trials against sham procedures. However, the role of LI-ESWT in ED caused by radical prostatectomy (RP) is still questionable because this type of ED was excluded from nearly all clinical studies; it has been investigated in only a few small single-arm trials. This review summarizes preclinical studies on mechanisms of action of LI-ESWT for ED and neurological diseases to explore the potential of this treatment for nerve-impaired ED after RP.

PMID:
29180799
DOI:
10.1038/s41443-017-0002-6
[Indexed for MEDLINE]

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