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Am J Dent. 2017 Aug;30(4):179-184.

Effects of riboflavin, calcium-phosphate layer and adhesive system on stress-strain behavior of demineralized dentin.

Author information

1
Division of Cariology and Endodontology, of Dental Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
2
Center for Applied Biotechnology and Molecular Medicine -CABMM, University of Zurich, Switzerland.
3
Faculty of Medicine, University of Geneva, Geneva, Switzerland.
4
Department of Opthamology, University of Southern California, Los Angeles, CA, USA.
5
Department of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
6
The Forsyth Institute, Cambridge, Massachusetts, USA.

Abstract

PURPOSE:

To evaluate if three dentin treatments improved mechanical properties of demineralized dentin.

METHODS:

Dentin slices were demineralized and treated with a universal adhesive, Scotchbond Universal (SBU), a cross-linker, Riboflavin (RF), and a calcium phosphate-based product, Teethmate (TM). The groups (n= 8 per group) were: Group 1: SBU, Group 2: RF + SBU, Group 3: RF + TM + SBU. Tensile tests were performed; stress/strain curves and E modulus were calculated. Differences between groups were assessed by one-way ANOVA and Duncan post hoc test.

RESULTS:

At high strains, no significant differences in E moduli were observed between dentin specimens treated only with SBU and those treated with RF + SBU. A significantly higher E modulus was observed in dentin specimens treated with RF + TM + SBU. In the presence of an adhesive system, crosslinking collagen with RF and TM addition significantly improved mechanical properties of dentin.

CLINICAL SIGNIFICANCE:

Restitution of mineral content into dentin, in addition to collagen strengthening, may significantly improve mechanical properties of previously demineralized dentin, when covered by an adhesive system in a reasonable clinical timeframe.

PMID:
29178698
[Indexed for MEDLINE]

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