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J Pediatr. 2017 Dec;191:96-102. doi: 10.1016/j.jpeds.2017.08.061.

Cardiac Biomarker Release after Endurance Exercise in Male and Female Adults and Adolescents.

Author information

1
Section of Physical Education and Sports, University of Zaragoza, Zaragoza, Spain.
2
School of Sports Organization, Autonomous University of Nuevo Leon, Monterrey, Mexico.
3
School of Sports Organization, Autonomous University of Nuevo Leon, Monterrey, Mexico. Electronic address: ricardo.navarroo@uanl.mx.
4
School of Biological Sciences, Autonomous University of Nuevo Leon, Monterrey, Mexico.
5
Department of Sports and Computer Science, Section of Physical Education and Sports, Universidad Pablo de Olavide, Sevilla, Spain.
6
Research Group Human Movement, University of Lleida, LLeida, Spain.
7
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Abstract

OBJECTIVES:

To compare the responses of high-sensitivity cardiac troponin T (hs-cTnT) and NH2-terminal probrain natriuretic peptide (NT-proBNP) after 60 minutes of swimming in male and female adults and adolescents with different pubertal status.

STUDY DESIGN:

Adolescent swimmers (25 male and 25 female) and adult swimmers (7 male and 9 female) participated in a 60-minute maximal swimming test with serial assessment of hs-cTnT and NT-proBNP at rest, immediately postexercise, and at 1, 3, 6, 12, and 24 hours postexercise. Adolescents were classified according to pubertal status: Tanner stages 3 (n = 14), 4 (n = 22), and 5 (n = 14).

RESULTS:

Exercise resulted in an increase in both biomarkers. hs-cTnT responses to exercise were similar in adolescents with different pubertal status and adults, although there was substantial individual variability in peak hs-cTnT, with the upper reference limit exceeding in 62% of the participants. Postexercise kinetics for hs-cTnT were largely consistent across all groups with a return to near baseline levels 24 hours postexercise. The male participants showed higher values of hs-cTnT at baseline and postexercise. All groups had similar NT-proBNP responses to acute exercise and recovery. One swimmer exceeded the upper reference limit for NT-proBNP.

CONCLUSIONS:

An exercise-associated increase in hs-cTnT and NT-proBNP occurred in response to a 60-minute maximal swimming test that was independent of pubertal status/adolescent vs adults. The present data also suggests that baseline and postexercise hs-cTnT values are higher in male compared with female, with no sex differences in NT-proBNP values.

KEYWORDS:

NH2-terminal pro-brain natriuretic peptide; Tanner stage; high-sensitivity cardiac troponin T; sex; swimming

PMID:
29173327
DOI:
10.1016/j.jpeds.2017.08.061
[Indexed for MEDLINE]

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