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Actas Esp Psiquiatr. 2017 Sep;45(Supplement):8-15. Epub 2017 Sep 1.

Nutritional supplements in depressive disorders.

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Biomedical Research Centre in Mental Health Network (CIBERSAM) G10, Spain Psychiatry Department. BioAraba, Health Research Institute, Araba University Hospital, Vitoria, Spain University of the Basque Country, Spain.


There is increasing evidence about the role of nutrients in mental health. An adequate intake of nutrients contributes to better overall health and mental health in particular. Major depression is a severe mental illness with a high prevalence for which effective treatments exist but not in all cases the patient’s remission is achieved. Therefore, it is increasingly aimed at optimizing the supply of nutrients necessary for adequate brain functioning as adjunctive therapy to antidepressant treatment in depressive disorders. In this article we review those nutrients that have been related to depression: Omega-3 fatty acids, B vitamins, s-adenosylmethionine, tryptophan, magnesium, zinc and probiotics.

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