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Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(10):131-135. doi: 10.17116/jnevro2017117101131-135.

[Nitric oxide: from the mechanism of action to pharmacological effects in cerebrovascular diseases].

[Article in Russian; Abstract available in Russian from the publisher]

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Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.


in English, Russian

The article presents the data of studies of nitric oxide (NO) in the pathogenesis of cerebrovascular diseases. It is emphasized that endothelial dysfunction contributes to the formation of cerebrovascular diseases. Generalized data on preparations with endothelioprotective effect, as well as own data on the use of the preparation 'Divaza' in patients of middle and advanced age with chronic cerebrovascular disease are given.


cerebrovascular diseases; divazа; endothelial dysfunction; nitric oxide; prooxidant and antioxidant systems; therapeutic strategies

[Indexed for MEDLINE]

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