Format

Send to

Choose Destination
Biochem Biophys Res Commun. 1989 Jan 31;158(2):569-75.

Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.

Author information

1
Institute for Molecular and Cellular Biology, Osaka University, Suita, Japan.

Abstract

The cDNA clone encoding human prechymotrypsinogen was isolated from a human pancreas cDNA library and its nucleotide sequence was determined. The sequence consists of a 16 bp 5' non-coding region, a 789 bp amino acid coding region and a 60 bp 3' non-coding region. The predicted product consists of 263 amino acids, including 18 amino acids for a signal peptide and 15 amino acids possible for an activation peptide. Southern blot analyses using the cloned cDNA as a probe revealed that human genomic DNA carries at least two genes that are related to chymotrypsinogen.

PMID:
2917002
DOI:
10.1016/s0006-291x(89)80087-7
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center