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J Cosmet Dermatol. 2018 Jun;17(3):523-526. doi: 10.1111/jocd.12456. Epub 2017 Nov 21.

Serum homocysteine levels in acne patients.

Author information

1
Department of Dermatology, Clinical Research Center, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
2
Clinical Research Center, Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, China.

Abstract

OBJECTIVE:

This study was designed to investigate serum homocysteine (HCY) levels in acne patients.

METHODS:

Acne patients (n = 124) and healthy volunteers (n = 70), matched in terms of both age and sex, were enrolled. Serum HCY levels for all subjects were measured by a clinical laboratory.

RESULTS:

Serum HCY levels in male and female patients with severe and moderate acne were significantly higher than in the healthy control group (P < .05). The constituent ratio of male and female acne patients with HCY above the normal range (10 mmol/L) was significantly higher than the healthy control group. The severity of acne patients was positively correlated with serum homocysteine concentration, (P < .01).

CONCLUSION:

Hyperhomocysteinemia may be an independent risk factor for acne vulgaris. Detection of serum HCY is important for acne patients.

KEYWORDS:

acne vulgaris; folate; homocysteine; vitamin B12; vitamin B6

PMID:
29159884
DOI:
10.1111/jocd.12456
[Indexed for MEDLINE]

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