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Child Adolesc Psychiatr Clin N Am. 2018 Jan;27(1):37-52. doi: 10.1016/j.chc.2017.08.011. Epub 2017 Oct 20.

Evaluation and Management of Autoimmune Encephalitis: A Clinical Overview for the Practicing Child Psychiatrist.

Author information

1
Department of Psychiatry, Division of Child and Family Mental Health and Developmental Neurosciences, Duke University, Durham, NC, USA; Autoimmune Brain Disease Program, Department of Pediatrics, Duke University, Durham, NC, USA. Electronic address: Genalynne.mooneyham@duke.edu.
2
Autoimmune Brain Disease Program, Department of Pediatrics, Neurology Division, Duke University, Durham, NC, USA.
3
Autoimmune Brain Disease Program, Department of Pediatrics, Rheumatology Division, Duke University, Durham, NC, USA.

Abstract

Medical conditions that present with psychiatric symptoms are becoming increasingly well-recognized in response to the emergence of the field of neuroimmunology. As the availability of testing for novel antineuronal antibodies has increased, so too has the clinical awareness of this diagnostic spectrum. Psychiatrists may have little exposure to this area of expertise, yet may be called on to assist in the diagnosis and treatment of patients with complex neuropsychiatric syndromes secondary to autoimmune encephalitis. This article summarizes the evaluation and management of patients with autoimmune encephalitis and describes emerging patterns in phenotype recognition.

KEYWORDS:

Anti-NMDA; Antineuronal antibodies; Autoimmune brain disorders; Autoimmune encephalitis; Limbic encephalitis

PMID:
29157501
DOI:
10.1016/j.chc.2017.08.011
[Indexed for MEDLINE]

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