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J Cancer. 2017 Sep 20;8(17):3416-3429. doi: 10.7150/jca.21058. eCollection 2017.

Phycocyanin: A Potential Drug for Cancer Treatment.

Author information

1
Department of Genetics and Cell Biology, Basic medical college, 308 Ningxia Road, Qingdao University, Qingdao, China, 266071.
2
Basic medical college, 308 Ningxia Road, Qingdao University, Qingdao, China, 266071.

Abstract

Phycocyanin isolated from marine organisms has the characteristics of high efficiency and low toxicity, and it can be used as a functional food. It has been reported that phycocyanin has anti-oxidative function, anti-inflammatory activity, anti-cancer function, immune enhancement function, liver and kidney protection pharmacological effects. Thus, phycocyanin has an important development and utilization as a potential drug, and phycocyanin has become a new hot spot in the field of drug research. So far, there are more and more studies have shown that phycocyanin has the anti-cancer effect, which can block the proliferation of cancer cells and kill cancer cells. Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, thereby phycocyanin can serve as a promising anti-cancer agent. This review discusses the therapeutic use of phycocyanin and focuses on the latest advances of phycocyanin as a promising anti-cancer drug.

KEYWORDS:

Apoptosis; Autophagy; Cancer; Cell cycle arrest.; Phycocyanin

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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