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J Invertebr Pathol. 1989 Jan;53(1):32-40.

Leukemia cell specific protein of the bivalve mollusc Mya arenaria.

Erratum in

  • J Invertebr Pathol 1989 Jul;54(1):137.


Soft shell clams, Mya arenaria, develop leukemias in the hemolymph which are fatal. Tissue sections and hemolymph samples from normal and tumor-bearing clams were tested with an anti-leukemic cell specific monoclonal antibody (Mab) "IEII." Evaluation of leukemic cells and normal hemocytes by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analyses showed that Mab IEII bound to a large protein of approximately 200 kDa from the tumor cell, but not from the normal cell preparation.

[Indexed for MEDLINE]

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