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J Community Hosp Intern Med Perspect. 2017 Oct 18;7(5):300-302. doi: 10.1080/20009666.2017.1374107. eCollection 2017.

Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital.

Author information

1
Department of Pulmonary Medicine, Jamaica Hospital Medical Center, Jamaica, NY, USA.
2
Department of Clinical Research, Jamaica Hospital Medical Center, Jamaica, NY, USA.

Abstract

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia caused by MRSA. Objectives: To review the use of ceftaroline in MRSA pneumonia in a US hospital and evaluate its clinical success. Methods: A retrospective study was conducted in an urban community hospital assessing the use of ceftaroline for MRSA pneumonia. Results: The clinical success was comparable to the currently approved treatment for MRSA pneumonia. Conclusion: The results of our study showed a favorable result for the treatment of MRSA pneumonia. Well-designed studies need to be performed for further validation of these results.

KEYWORDS:

Methicillin-resistant Staphylococcus aureus; ceftaroline; clinical success; pneumonia; retrospective study

Conflict of interest statement

No potential conflict of interest was reported by the authors.

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